See body Related DreamsThumb Referring to a particular situation, thumbs up is positive; thumbs down is negativeThumb 1. Direction, or direction in life. 2. Indicator of life or death (as in gladiator games). 3. Mobility.Thumb 1. Dexterity, ability to “handle” things. 2. Success (large thumb). 3. Dependence on others for mobility (as in “hitching a ride”). 4. Direction in life.